AGGRENOX is a prescription medication used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

Taking AGGRENOX

Your doctor may have prescribed AGGRENOX because it works to make small cells in the blood called platelets less sticky. This makes it less likely that those platelets will clump together and form a clot that can block blood flow to the brain—the cause of 87% of strokes .

That's why it's important to keep taking AGGRENOX as your doctor prescribed. Below, you'll find important information for starting—and continuing—treatment with AGGRENOX.

Before starting treatment

It's important to share certain information with your doctor before you begin treatment with AGGRENOX. Your doctor should know:

  • Any medication you are taking, or plan to take in the future. This includes prescription and over-the-counter medication as well as vitamins and herbal supplements.
  • Any allergies or illnesses you may have. Your doctor can help you decide if AGGRENOX is right for you.
  • If you have a history of stomach ulcers or drink more than 3 alcoholic drinks a day.
  • If you are or think you might be pregnant. AGGRENOX may not be right for you.

Who should not take AGGRENOX? AGGRENOX contains aspirin. So some people should not take AGGRENOX or should be aware of the risks associated with aspirin. AGGRENOX should be avoided by:

  • Patients who are hypersensitive to any of the components of AGGRENOX or who are allergic to non-steroidal anti-inflammatory drugs (NSAIDs).
  • Patients with asthma in combination with runny nose and nasal polyps.
  • Women in the third trimester of pregnancy.
  • Children or teenagers with viral infections because of the risk of Reye's syndrome.
  • Patients with a history of stomach ulcers. These patients should avoid using aspirin.

In addition, patients who consume 3 or more alcoholic drinks every day should be aware of the bleeding risks involved with chronic, heavy alcohol use while taking aspirin.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. AGGRENOX and other medicines may affect each other, causing side effects.

AGGRENOX is not right for everyone. Talk to your doctor to find out if AGGRENOX is right for you. Our guide to working with your doctor—which includes questions to ask about AGGRENOX—may help.

During treatment

Always take AGGRENOX exactly how your doctor prescribed. When you do, be sure to follow these instructions:

  • Swallow AGGRENOX whole. Do not crush or chew the capsules.
  • You can take your AGGRENOX with or without food.
  • If you miss a dose, take your next dose at the usual time. Do not take 2 doses at one time.

If you take more AGGRENOX (overdose) than prescribed, call your healthcare provider or the Poison Control Center to get emergency help right away.

It's also important to know the possible side effects of AGGRENOX—and report any side effects to your doctor right away.

What if you experience headaches during treatment? Headaches are not uncommon when you first start taking AGGRENOX, but often lessen as treatment continues. Tell your healthcare provider if you have a severe headache. Your healthcare provider may change the instructions for taking AGGRENOX.

How long should you stay on AGGRENOX? You should never stop taking your medication without talking to your doctor first. Once you've had a TIA or stroke caused by a blood clot, your risk of another stroke is increased.

AGGRENOX can help reduce the risk by making small cells called platelets in the blood less sticky. This means they're less likely to clump together and form blood clots—the cause of 87% of strokes.

In fact, in a clinical trial:

  • Over 90% of patients on AGGRENOX remained stroke-free for 2 years (1493 patients out of a total of 1650).
  • Patients taking AGGRENOX twice daily were 22% less likely to have a stroke than patients taking low-dose aspirin (25 mg twice daily) alone.
  • AGGRENOX was twice as effective as low-dose aspirin (25 mg twice daily) at reducing the risk of a subsequent stroke when tested against a sugar pill.

Other things you can do to help reduce your stroke risk

Taking AGGRENOX exactly as prescribed by your doctor is important. But there may be more you can do to help reduce your risk of a subsequent stroke.

Be sure to talk with your doctor about your lifestyle, including diet and exercise. And keep track of the healthy changes you're making so you can share your results and challenges with your doctor. This information will help your doctor understand your needs and make decisions about your treatment plan.

Next:  Lifestyle Changes

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Helpful resources

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IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.

IMPORTANT SAFETY INFORMATION

EXPAND SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.