AGGRENOX is a prescription medication used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

Safety and Side Effects

Know the safety and side effects of AGGRENOX

Some people who take AGGRENOX may experience side effects. The most common side effects of AGGRENOX include headache, upset stomach, and diarrhea. Because AGGRENOX contains aspirin, the risk of bleeding is increased and it may take longer to stop bleeding.

These are not all the possible side effects of AGGRENOX. Tell your healthcare provider or pharmacist if you have any side effect that bothers you or that does not go away.

Know what to do if you experience headaches during treatment

Headaches are not uncommon when you first start taking AGGRENOX—especially within the first month—but often lessen as treatment continues. Tell your healthcare provider if you have a severe or intolerable headache. Your healthcare provider may change the instructions for taking AGGRENOX.

AGGRENOX may cause serious side effects, including:

  • Increased risk of bleeding. You may bleed more easily during AGGRENOX treatment, and it may take longer than usual for bleeding to stop. This can include:
    • Bleeding into your brain (intracranial hemorrhage). This can be a medical emergency. Get medical help right away if you have any of these symptoms while taking AGGRENOX:
      • Severe headache with drowsiness
      • Confusion or memory change
      • Passing out (becoming unconscious)
    • Bleeding in your stomach or intestine.
      • Stomach pain
      • Heartburn or nausea
      • Vomiting blood or vomit that looks like “coffee grounds”
      • Red or bloody stools
      • Black stools that look like tar
  • New or worsening chest pain in some people with heart disease. Tell your doctor if you have new chest pain or have any change in your chest pain during treatment with AGGRENOX.
  • Liver problems, including increased liver function tests and liver failure. Tell your doctor if you have any of these symptoms of a liver problem while taking AGGRENOX:
    • Loss of appetite
    • Pale-colored stool
    • Stomach-area (abdominal) pain
    • Yellowing of your skin or whites of your eyes
    • Dark urine
    • Itching

Call your doctor right away if you have any of the symptoms listed above.

Next:  Paying for AGGRENOX

Learn about AGGRENOX

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Helpful resources

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IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.

IMPORTANT SAFETY INFORMATION

EXPAND SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.