AGGRENOX is a prescription medication used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX Reduces Stroke Risk

You'll be glad to know that AGGRENOX helps reduce the risk of stroke in patients who had a TIA or stroke due to a blood clot. But you may be wondering—how does it work?

Blood clots: The cause of most strokes

In most cases, a stroke occurs when a blood clot blocks a blood vessel and cuts off the blood supply, along with oxygen and nutrients it carries, to a part of the brain. Blood clots form when certain blood cells, called platelets, clump together. This type of stroke is known as an ischemic stroke.

When this happens, blood cannot get through to a section of the brain, so that part of the brain's oxygen supply is cut off. Within minutes, those brain cells die and abilities controlled by those cells are lost. A TIA is a brief episode of stroke-like symptoms, with no lasting brain cell damage.

This is why your doctor may have prescribed AGGRENOX—to reduce the likelihood that you will have a blood clot that can cause a stroke.

AGGRENOX works by combining 2 medications

AGGRENOX combines 2 medications—aspirin and extended-release dipyridamole. Both medications are known as antiplatelet agents.

Platelets are cells in your blood that stick together to help your blood clot. Antiplatelet agents work together to make platelets in the blood less sticky. That means they're less likely to clump together and form blood clots–the cause of 87% of strokes.

Together, the 2 antiplatelet agents in AGGRENOX work better than either medication alone at reducing the risk of a future stroke. In fact, in a clinical study:

  • Over 90% of patients taking AGGRENOX remained stroke-free for 2 years (1493 patients out of a total of 1650).
  • Patients taking AGGRENOX twice daily were 22% less likely to have a stroke than patients taking low-dose aspirin (25 mg twice daily) alone.
  • AGGRENOX was twice as effective as low-dose aspirin (25 mg twice daily) at reducing the risk of a subsequent stroke when tested against a sugar pill.

Next:  Talking With Your Doctor

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IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.

IMPORTANT SAFETY INFORMATION

EXPAND SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.