AGGRENOX is a prescription medication used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

About Stroke and TIA

Experiencing a stroke or TIA (your doctor may have called it a transient ischemic attack or "mini-stroke") can be overwhelming. Afterward, it's not easy to know what to do. If you experienced a stroke, you may be working to recover from its lasting effects. In addition, you may be worried about the future, especially about whether it can happen again. The following information may help you understand what you've just experienced.

What happens during a stroke?

A stroke is caused by a stoppage of blood flow to a section of the brain. Brain cells are starved of the blood and oxygen they need to function. Within minutes, those brain cells begin to die, and the functions they control are lost. A stroke can happen anywhere in the brain. It can be large or small, and it can affect many different functions, from speech to movement to memory.

The most common type of stroke is an ischemic stroke, accounting for about 87% of all strokes. An ischemic stroke occurs when a blood clot blocks an artery or other blood vessel, blocking blood flow to the brain.

This type of stroke may be preceded by a TIA (transient ischemic attack or "mini-stroke"). In fact, your risk of having a stroke after a TIA is highest in the first week after having the TIA. With a TIA, the blockage is temporary and most symptoms go away in less than an hour without leaving any permanent damage.

Understanding the risk of another stroke

Once you've had a TIA or stroke caused by a blood clot, you are at an increased risk of a future stroke.

  • Stroke is the fourth leading cause of death and a leading cause of serious, long-term adult disability in the U.S.
  • If another stroke occurs, there is up to a 10% chance that it will happen 30 days after the first stroke.
  • Gender and race matter:
    • Women experience approximately 55,000 more strokes each year than men.
    • African Americans experience more than twice as many strokes as Caucasians.
    • Hispanic or Latino men have a higher risk of stroke than Caucasian men.

Having FDA-approved AGGRENOX as a part of your treatment plan may help reduce the risk of a future stroke. That's because AGGRENOX works by making platelets in the blood less sticky. This means they're less likely to clump together and form a blood clot that can cause a stroke.

During a 24-month clinical study in patients who have had a TIA or stroke due to a blood clot, over 90% of patients on AGGRENOX remained stroke-free (1493 patients out of a total of 1650). And patients taking AGGRENOX twice daily were 22% less likely to have a stroke than patients taking low-dose aspirin (25 mg twice daily) alone.

Next: Symptoms & Long-term Effects

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IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.

IMPORTANT SAFETY INFORMATION

EXPAND SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a "mini-stroke" (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics ("water pills").

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Click here for full Prescribing Information including Patient Information.