Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a “mini-stroke” (transient ischemic attack or TIA) or stroke due to a blood clot.

About AGGRENOX

  • How AGGRENOX works

    AGGRENOX is a prescription medicine that is FDA approved to lower the risk of stroke in people who have had either a TIA (transient ischemic attack or “mini-stroke”) or stroke due to a blood clot.

    In most cases, a stroke occurs when a blood clot blocks a blood vessel and cuts off the blood supply, along with oxygen and nutrients it carries, to a part of the brain. Since the brain depends on blood, oxygen, and nutrients to function properly, this blockage causes that part of the brain—and the part of the body it controls—to stop working. TIAs are “warning strokes” that happen when a blood clot clogs an artery for a short time. Although TIAs only last a few minutes, they can be a sign of an impending major stroke.

    AGGRENOX combines 2 medications–aspirin and extended-release dipyridamole–into
    1 capsule. When taken twice daily, AGGRENOX makes small clot-forming cells in the blood (called platelets) less “sticky,” so they are less likely to clump together and form a blood clot. Together, the 2 medications in AGGRENOX work better at reducing the risk of a future stroke than either medication alone.

    In fact, in a clinical study:

    • Patients taking AGGRENOX twice daily were 22% less likely to have a stroke than patients taking low-dose aspirin (25 mg twice daily) alone

    • AGGRENOX was twice as effective as low-dose aspirin (25 mg twice daily) at reducing the risk of a subsequent stroke when tested against a sugar pill

    • Over 90% of patients taking AGGRENOX remained stroke-free for 2 years (1493 patients out of a total of 1650)

  • How to take AGGRENOX

    Always take AGGRENOX exactly how your doctor prescribed. Be sure to follow these instructions:

    • Swallow AGGRENOX whole. Do not crush or chew the capsules

    • You can take your AGGRENOX with or without food

    • If you miss a dose, take your next dose at the usual time. Do not take 2 doses at one time

    If you take more AGGRENOX than prescribed (overdose), call your healthcare provider or the Poison Control Center to get emergency help right away. It's also important to know the possible side effects of AGGRENOX—and report any side effects to your doctor right away.

    You should never stop taking your medication without talking to your doctor first. Once you've had a TIA or stroke caused by a blood clot, your risk of another stroke is increased.

    Before you begin treatment, it's important to share the information below with your doctor, and be aware of the risks of aspirin.

    Your doctor should know:

    • Any medication you are taking, or plan to take in the future. This includes prescription and over-the-counter medication, as well as vitamins and herbal supplements

    • Any allergies or illnesses you may have. Your doctor can help you decide if AGGRENOX is right for you

    • If you have a history of stomach ulcers or drink more than 3 alcoholic drinks a day

    • If you are or think you might be pregnant. AGGRENOX may not be right for you

    AGGRENOX contains aspirin. Some people should not take AGGRENOX or should be aware of the risks associated with aspirin. AGGRENOX should be avoided by:

    • Patients who are hypersensitive to any of the components of AGGRENOX or who are allergic to non-steroidal anti-inflammatory drugs (NSAIDs)

    • Patients with asthma in combination with runny nose and nasal polyps

    • Women in the third trimester of pregnancy

    • Children or teenagers with viral infections, because of the risk of Reye's syndrome

    • Patients with a history of stomach ulcers. These patients should avoid using aspirin

    In addition, patients who consume 3 or more alcoholic drinks every day should be aware of the bleeding risks involved with chronic, heavy alcohol use while taking aspirin.

    AGGRENOX is not right for everyone. Talk to your doctor to find out if AGGRENOX is right for you.

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LEARN ABOUT SAFETY AND SIDE EFFECTS

INDICATIONS AND IMPORTANT SAFETY INFORMATION

EXPAND SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a “mini-stroke” (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics (“water pills”).

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
1-800-FDA-1088.

Please see full Prescribing Information, including Patient Information.

INDICATIONS AND IMPORTANT SAFETY INFORMATION

Aggrenox® (aspirin/extended-release dipyridamole) 25 mg/200 mg capsules is a prescription medicine used to lower the risk of stroke in people who have had a “mini-stroke” (transient ischemic attack or TIA) or stroke due to a blood clot.

AGGRENOX should be avoided in patients who are allergic to any ingredient in AGGRENOX, or allergic to non-steroidal anti-inflammatory drugs (NSAIDs), or who have the combination of asthma, runny nose, and nasal polyps. AGGRENOX should not be given to a child or teenager.

AGGRENOX increases the risk of bleeding, including bleeding into the brain, stomach or intestines. Any bleeding you have may take longer to stop when you are taking AGGRENOX.

AGGRENOX should be avoided by patients with a history of stomach ulcers or those who drink three or more alcoholic drinks a day, as these can increase the risk of bleeding. Patients should tell their doctor about all medicines they are taking, especially blood thinners, heparin, warfarin, NSAIDs, heart medicines, or medicines for high blood pressure, including diuretics (“water pills”).

AGGRENOX should be avoided during pregnancy, especially in the third trimester. AGGRENOX should be avoided in patients with severe liver or kidney problems. The most common side effects of AGGRENOX are headache, upset stomach, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
1-800-FDA-1088.

Please see full Prescribing Information, including Patient Information.

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You are now leaving a Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) site. BIPI is not responsible for the way information is processed by sites linked to this one. Please review those sites’ privacy policies and terms of use to understand how your information will be processed. Linking to any other site is at your own risk.