• Understanding the Risk of Another Stroke
• How AGGRENOX Reduces Stroke Risk
• Talking with Your Doctor

How AGGRENOX Reduces Stroke Risk

Blood clots: The cause of most strokes.

In most cases, a stroke occurs when a blood clot blocks a blood vessel and cuts off the blood supply, along with oxygen and nutrients it carries, to a part of the brain. Blood clots form when certain blood cells, called platelets, clump together. This type of stroke is known as an ischemic stroke.

When this happens, blood cannot get through to a section of the brain, so that part of the brain’s oxygen supply is cut off. Within minutes, those brain cells die and abilities controlled by those cells are lost. A TIA is a brief episode of stroke-like symptoms, with no lasting brain cell damage.

AGGRENOX works by combining two medications—low-dose aspirin and extended-release dipyridamole.

AGGRENOX combines two medications—aspirin and extended-release dipyridamole. This combination is better than either medication alone at reducing the risk of another stroke. The 2 medications are known as antiplatelets, and they work together to make platelets in the blood less sticky, so they are less likely to clump together and form blood clots.

Once you’ve had a TIA (transient ischemic attack or "mini-stroke") or stroke due to a blood clot, you are at an increased risk for a subsequent stroke. Taking AGGRENOX may help lower the risk.

AGGRENOX helps reduce the risk of stroke in patients who had a TIA or stroke due to a blood clot.

• More than 90% of patients taking AGGRENOX remained stroke-free for 2 years (1493 out of a total of 1650).
• AGGRENOX taken twice daily helped lower the risk of stroke by 22% compared to low-dose aspirin (25 mg twice daily) alone over 2 years.