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Clinical Studies

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Good Science for Preventing
Stroke’s early warning — TIA
Stroke and TIA Facts
  • Up to 30% of stroke survivors are disabled — it is a leading cause of long-term adult disability in the U.S.1
  • The most common vascular event in the first few years after transient ischemic attack (TIA)/stroke is a recurrent stroke.2
  • 50% of all stroke/TIA patients will have a repeat event within one year.1
  • Unlike a stroke, a TIA usually lasts only a few minutes and there is no permanent damage to the brain.
Common Signs and Symptoms4
  • Brief period of weakness or numbness of the face, arm, or leg, especially on one side of the body
  • Brief period of confusion or trouble speaking or understanding
  • Trouble seeing in one or both eyes for a brief period of time
  • Trouble walking, dizziness, or loss of balance or coordination for a brief period of time
  • Brief period of severe headache with no known cause
Urgency to Treat
  • Nearly 1 in 5 TIA/stroke patients is at risk of a repeat event within 3 months.3
  • Risk of recurrent TIA/stroke within 6 months after a TIA is 26%.6
  • About 8% of strokes that occur after a TIA strike within 7 days.3
  • Up to 25% of patients will die within a year of a TIA.1
Need for Patient Education

Because of its short duration and lack of permanent effects, a TIA is easy for a patient to dismiss or forget.

Download these materials to further support your efforts to educate your patients on TIA signs and symptoms and help them better understand the relationship between TIA and recurrent stroke.

TIA Factsheet

TIA Patient Brochure

Physician Guidance

National Stroke Association

Aspirin (50 mg) plus extended-release dipyridamole (200 mg twice daily) [AGGRENOX] is a first-choice option to reduce the risk of stroke following a noncardioembolic TIA. (Category 1)7

American Heart Association

On the basis of comparative clinical studies, the combination of aspirin and extended-release dipyridamole is recommended over aspirin alone. (Class IIa, Level of Evidence A)8

Read more at my.americanheart.org.

American College of Chest...

In patients with known noncardioembolic stroke or TIA, the combination of aspirin and extended-release dipyridamole (25 mg/200 mg BID) is recommended over aspirin (Grade 2A)9

Clinical Studies

  • AGGRENOX prevents twice as many recurrent strokes as aspirin…10 Journal of the Neurological Sciences 1996;143:1-13 Details
  • AGGRENOX is especially effective for high risk patients…11 Arch Neurol. 2005;62:403-408 Details
  • AGGRENOX has been proven safe and effective for all recurrent stroke patients…10 Journal of the Neurological Sciences 1996;143:1-13 Details