Two powerful medicines that work like a team

The most common type of stroke - ischemic stroke - happens when a blood clot blocks damaged blood vessels in or leading to the brain. Blood clots are formed by platelets clumping together to plug holes in these damaged blood vessels.

AGGRENOX is indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis. AGGRENOX contains two effective medicines:

Aspirin works by reducing the production of prostaglandins. These are natural substances in the body that help platelets stick together to form blood clots. Dipyridamole works in a different way to prevent clots from forming.

Together in AGGRENOX, these two ingredients are more effective that either one alone. In fact, AGGRENOX is twice as good as aspirin at helping to prevent recurrent TIA/stroke.

Aspirin and generic dipyridamole cannot be used as a substitute for AGGRENOX. When these two medicines are combined in the AGGRENOX capsule, they create a powerful combination treatment that helps prevent clots from forming and causing a stroke.

WHAT’S RELATED?

You may also be interested in reading:

Managing Risk Factors
AGGRENOX Effectiveness

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Important Information about AGGRENOX

AGGRENOX is indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.

The most common adverse event with AGGRENOX was headache (39.2% vs 32.9% with placebo), which was more frequent at the onset of therapy but diminished over time. In ESPS 2, GI bleeding with AGGRENOX was comparable to aspirin (4.1% vs 3.2%) and the incidence of intracranial hemorrhage was nine (9) patients (0.6%) in the AGGRENOX group, six (6) patients (0.5%) in the extended-release dipyridamole group, six (6) patients (0.4%) in the aspirin group and seven (7) patients (0.4%) in the placebo group.

AGGRENOX contains aspirin. Patients who consume three or more alcoholic drinks every day should be counseled about the bleeding risks involved with chronic, heavy alcohol use while taking aspirin. Even low doses of aspirin can increase bleeding time, which can adversely affect patients with bleeding disorders. Patients with a history of active peptic ulcer disease should avoid using aspirin, which can cause gastric mucosal irritation and bleeding. AGGRENOX should be avoided in the third trimester of pregnancy.

Click here for full AGGRENOX Prescribing Information.